Research
Clinical research at the intersection of imaging, fluid balance, and renal medicine.
Honours manuscript
Fluid overload is common in end-stage kidney disease and difficult to gauge at the bedside. This project used CT-derived lung density as a quantitative imaging biomarker of pulmonary water in people on dialysis — linking radiology metrics to the haemodynamic and volume challenges of renal replacement therapy.
In chronic kidney disease, small shifts in extracellular fluid can tip patients toward pulmonary oedema long before symptoms are obvious. Traditional assessment — weights, JVP, crackles — is useful but imperfect.
CT offers voxel-level quantification of lung tissue density, which rises as interstitial and alveolar water accumulate. Applying that signal to a dialysis cohort asks whether imaging can complement clinical judgement when dry weight and ultrafiltration targets are being set.
